How Cigarette Smoking Causes Disease and Amputation of Palms Arms and legs

Cigarette smoking itself is not habit forming, but it is liable for releasing dopamine, a neurotransmitter associated with pleasure and reinforcements in the brain, thus inducing habit forming , บุหรี่ไฟฟ้า tendencies in humans. Cigarette smoking is a chemical found in tobacco leaf, the main ingredient in using tobacco and is said to cause addiction and disease in cigarette smokers, (World Health Organization (WHO)).

Cigarette smoking mimics the actions of acetylcholine, a naturally occurring neurotransmitter in the central nervous system and the nerve-muscle junction of skeletal muscles. Acetylcholine is liable for excitability, which then increase heart rate, alertness, and reaction times, (Psychopharmacology (Berl). 1989; 97(2): 257-61. ). Because acetylcholine and cigarette smoking are chemically similar, they trigger the same cholinergic receptors in the brain. The nicotine-acetylcholine receptors consist of lack of feeling endings that release dopamine when coupled or bind with cigarette smoking or acetylcholine. Receptors are like cups of coffee having the exact dimensions that will fit a neurotransmitter molecule, such as acetylcholine.

The cup itself is lined with lack of feeling endings (tips of neurons). It is these lack of feeling endings that release dopamine when the neurotransmitter acetylcholine binds with the cup-like acetylcholine receptors (cholinergic receptors). A reinforcing and reward phenomenon of dopamine develops because the dopamine that is released from the lack of feeling endings initiates a feeling of pleasure in the plaintiff’s brain. The reinforcement mechanism is initiated when the brain becomes addicted to the pleasure caused by the dopamine that is released from the cholinergic receptors. This means that the brain is constantly seeking to be pleasured. So, what will happen in the case of cigarette smokers is that they will continue to smoke cigarettes so the cigarette smoking from the cigarette can induce the release of dopamine in the brain, causing them to feel happy every time they smoke a cigarette, (Nature Reviews Neuroscience 7, 967-975 (December 2006)).

The first time cigarette smokers reviewed using tobacco there were only a few cholinergic receptors available because the natural action of acetylcholine only needs the normal amount of receptors provided by nature to do its job. However, the increase concentration of cigarette smoking available caused the normal amounts of cholinergic receptors to become desensitized to the presence of the increased number of cigarette smoking in the cholinergic receptors. This desensitization causes the production or growth and development of more cholinergic receptors. These extra cholinergic receptors will soon become desensitized from the excess cigarette smoking available. Such processes occur until equilibrium is reached. Equilibrium is reached when cigarette smokers decide on the amount of using tobacco they will consume or smoke in a given day. At this time, a fixed amount of receptors will be available for the addiction to continue. Smokers will normally say they smoke one or two provides per day. They said so because of the amount of receptors available to accommodate two provides of using tobacco in a day.

A detrimental effect of all this is the fact that such large amounts of cholinergic receptors are now available and famished for cigarette smoking. So, they can stimulate dopamine to pleasure the cigarette smoker. That’s why cigarette smokers employ a difficult time quitting. The best approach therefore for a cigarette smoker to use in quitting is to gradually cut back on the amount of using tobacco reviewed in a given time interval.

In addition to the dopamine-inducing effect of cigarette smoking, is the speeding-up of the heart rate by cigarette smoking every time a cigarette is reviewed. From a medical perspective, constantly having an artificial increase in heart rate isn’t recommended either. For starters, a constant increase in heart rate by drugs such as cigarette smoking can cause heart problems, (WHO).

According to the World Health Organization, tobacco use leads to diseases impacting on the heart and bronchi, such as heart attacks, strokes, chronic obstructive pulmonary disease (COPD), emphysema, and cancer. Most cigarette evoked cancers are lung cancer, cancers of the larynx, mouth, and pancreas. Cigarettes also causes myocardial infarctions, peripheral vascular disease and hypertension. The world Health Organization estimates that tobacco is liable for about 5. 4 million deaths in 2004 and about 100 million deaths during the the twentieth century.

In addition to its habit forming effects on the central nervous system, cigarettes contains a multitude of cancer-causing agents. They work by binding to DNA causing many genetic mutations. Cigarette smoking could be the main the most likely culprit that is doing the binding to DNA causing genetic mutations, which leads to cancer. Cigarette smoking is said to disrupt the natural processes of apoptosis (programmed cell death) by binding to DNA in cells, (National Institute of Health (NIH)). Costly cells consist of junk DNA and other waste materials. When apoptosis is inhibited, natural cell death does not occur; instead, costly cells are allowed to proliferate or grow larger, uncontrollably. This is just what happens in cancer and exactly why cigarette smokers are more susceptible to developing cancers.

When apoptosis is uncontrollably triggered by chemicals, such as cigarette smoking, it causes normal cells to die off. This may perhaps be what is happening in the heart flesh of cigarette smokers who suffer from heart problems and could also be what is taking place in the extremities of cigarette smokers, who often complain of excessive coldness in their palms, arms, toes, and legs, where circulation is lowest.

There are no existing studies to support this exact explanation. However, based on the comprehension of known scientific evidence of apoptosis and the increase in death rates of cigarette smokers, this hypothetical explanation has some credence; and will continue to have credence until proven otherwise! There is something fatal that is happening to cigarette smokers and cigarette smoking is one of the agents behind it.

The tar in cigarettes is also a realtor that sucks lifespan out of cigarette smokers. The lung of a cigarette smoker is just as black as the color of asphalt. It is like a severe little bit of burned up pot roast. This is why most cigarette smokers have difficulties breathing. It is next to impossible for air to pass freely down the airways of smokers. The sad thing is that it is difficult for cigarette smokers to give up. So, they continue down the road of deterioration, day after day, puffing on the silent killer–cigarette smoking.

One very important solution to quitting smoking is smoking one less cigarette a day or even one less cigarette in a month if one less cigarette a day is too steep of an adjustment to the fatal habit. If one normally smoking cigarettes a pack of using tobacco a day, that individual should remove one of those using tobacco and discard it–throw it in the waste can. Remember that the smoking of using tobacco started gradually. No one started smoking a pack of using tobacco a day in that awful beginning stage of smoking cigarettes. Smoking one less cigarette per a particular time frame will help eliminate the excessive cholinergic receptors that cigarette smoking so really needs.

Wellbutrin is another method for helping people to give up smoking. Wellbutrin is an antidepressant drug searched by people with depression. However, it is very potent in helping people kick the fatal habit of cigarettes. It can be taken while smoking, unlike other smoking cessation agents. Wellbutrin blocks cigarette smoking receptors and weakens the action of dopamine reuptake by neurons, (J Pharmacol Exp Ther. 2000 Oct; 295(1): 321-7. ).

Cigarette smokers who are interested in quitting should implement an exercise program in their schedule because the lack of cigarette smoking in ex-cigarette smokers causes weight-gain. How do we know this? Former cigarette smokers who kicked the habit complain of putting on weight after they quit smoking. Ask any ex-cigarette smoker. One will hear the same thing. Cigarette smoking induces weight-loss in smokers. This is why most cigarette smokers are slim or slim. If a cigarette smoker is overweight while smoking cigarettes, then see your face will definitely seek medical attention because can actually a very dangerous medical condition lurking in the shadows.